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Recommendations when to order or not order the test. May include related or preferred tests.
Use when a diagnosis of essential thrombocythemia (ET) or primary myelofibrosis (PMF) is suspected.
New York DOH Approval Status
Indicates test has been approved by the New York State Department of Health.
This test is New York state approved.
Specimen Required
Patient PreparationInstructions patient must follow before/during specimen collection.
CollectSpecimen type to collect. May include collection media, tubes, kits, etc.
Whole blood or bone marrow in lavender (EDTA).
Specimen PreparationInstructions for specimen prep before/after collection and prior to transport.
Whole Blood: Do not freeze. Transport 5 mL whole blood. (Min: 1 mL) Bone Marrow: Do not freeze. Transport 3 mL bone marrow. (Min: 1 mL)
Storage/Transport TemperaturePreferred temperatures for storage prior to and during shipping to ARUP. See Stability for additional info.
Refrigerated.
Unacceptable ConditionsCommon conditions under which a specimen will be rejected.
Plasma, serum, FFPE tissue blocks/slides, or fresh or frozen tissue. Specimens collected in anticoagulants other than EDTA. Clotted or grossly hemolyzed specimens.
RemarksAdditional specimen collection, transport, or test submission information.
StabilityAcceptable times/temperatures for specimens. Times include storage and transport time to ARUP.
Refrigerated: 7 days; Frozen: Unacceptable
Methodology
Process(es) used to perform the test.
Droplet Digital PCR (ddPCR)/Capillary Electrophoresis
Performed
Days of the week the test is performed.
Varies
Reported
Expected turnaround time for a result, beginning when ARUP has received the specimen.
3-15 days
Reference Interval
Normal range/expected value(s) for a specific disease state. May also include abnormal ranges.
Interpretive Data
May include disease information, patient result explanation, recommendations, or details of testing.
Refer to report.
Compliance Category
Laboratory Developed Test (LDT)
Note
Additional information related to the test.
If JAK2 qualitative is reported as "Not Detected," then CALR Exon 9 Mutation Analysis by PCR and MPL Mutation Detection will be added. Additional charges apply.
The American Medical Association Current Procedural Terminology (CPT) codes published in ARUP's Laboratory Test Directory are provided for informational purposes only. The codes reflect our interpretation of CPT coding requirements based upon AMA guidelines published annually. CPT codes are provided only as guidance to assist clients with billing. ARUP strongly recommends that clients confirm CPT codes with their Medicare administrative contractor, as requirements may differ. CPT coding is the sole responsibility of the billing party. ARUP Laboratories assumes no responsibility for billing errors due to reliance on the CPT codes published.
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
Other names that describe the test. Synonyms.
CALR
MPL
JAK2 (V617F) Mutation by ddPCR, Qualitative With Reflex to CALR (Calreticulin) Exon 9 Mutation Analysis by PCR and MPL Mutation Detection
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